Spider-Man (2002)

When bitten by a genetically modified spider, a nerdy, shy, and awkward high school student gains spider-like abilities that he eventually must use to fight evil as a superhero after tragedy befalls his family. - Kenneth Chisholm

Based on Marvel Comics' superhero character, this is a story of Peter Parker who is a nerdy high-schooler. He was orphaned as a child, bullied by jocks, and can't confess his crush for his stunning neighborhood girl Mary Jane Watson. To say his life is "miserable" is an understatement. But one day while on an excursion to a laboratory a runaway radioactive spider bites him... and his life changes in a way no one could have imagined. Peter acquires a muscle-bound physique, clear vision, ability to cling to surfaces and crawl over walls, shooting webs from his wrist ... but the fun isn't going to last. An eccentric millionaire Norman Osborn administers a performance enhancing drug on himself and his maniacal alter ego Green Goblin emerges. Now Peter Parker has to become Spider-Man and take Green Goblin to the task... or else Goblin will kill him. They come face to face and the war begins in which only one of them will survive at the end. - Soumitra

On a school field trip, Peter Parker (Maguire) is bitten by a genetically modified spider. He wakes up the next morning with incredible powers. After witnessing the death of his uncle (Robertson), Parkers decides to put his new skills to use in order to rid the city of evil, but someone else has other plans. The Green Goblin (Dafoe) sees Spider-Man as a threat and must dispose of him. Even if it means the Goblin has to target Parker's Aunt (Harris) and the girl he secretly pines for (Dunst) - Film_Fan

Based off of the hit Marvel comics by Stan Lee, Spider-Man tells the story of a shy, nerdy high school teen, Peter Parker, who gets bitten by a radioactive spider, and soon gains super human abilities from it. But, after a tragic event occurs in his family, he realizes that his newly found powers should be used only for good. - Matt Deleon

A rather odd thing has just occurred in the life of nerdy high school student Peter Parker: after being bitten by a genetically modified spider, his body chemistry is altered mutagenically. He can now scale walls and ceilings, he has superhuman strength and super-fast reflexes, and he develops a precognitive sense that warns him of approaching danger. Adopting the name Spider-Man, Peter first uses his newfound powers to make money, but after his uncle is murdered at the hands of a criminal Peter failed to stop, he swears to use his powers to fight the evil that killed his uncle. At the same time, scientist and businessman Norman Osborn, after exposure to an experimental nerve gas, develops an alternate personality himself: the super-strong, psychotic Green Goblin! Peter Parker must now juggle three things in his life: his new job at a local newspaper under a perpetually on-edge employer, his battle against the evil Green Goblin, and his fight to win the affections of beautiful classmate Mary Jane Watson, against none other than his best friend Harry Osborn, son of Norman Osborn! Is this challenge too much for even the Amazing Spider-Man to handle? - Hammer2Fall